Abstract
Purpose: To evaluate the efficacy of pembrolizumab across multiple cancer types harboring different levels of whole-genome sequencing–based tumor mutational load (TML; total of nonsynonymous mutations across the genome) in patients included in the Drug Rediscovery Protocol (NCT02925234). Patients and Methods: Patients with solid, treatment-refractory, microsatellite-stable tumors were enrolled in cohort
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