Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis
Eijkemans, Marianne; Mommers, Monique; Harskamp-van Ginkel, Margreet W.; Vrijkotte, Tanja G.M.; Ludvigsson, Johnny; Faresjö, Åshild; Bergström, Anna; Ekström, Sandra; Grote, Veit; Koletzko, Berthold; Bønnelykke, Klaus; Eliasen, Anders Ulrik; Bager, Peter; Melbye, Mads; Annesi-Maesano, Isabella; Baïz, Nour; Barros, Henrique; Santos, Ana Cristina; Duijts, Liesbeth; Mensink-Bout, Sara M.; Flexeder, Claudia; Koletzko, Sibylle; Schikowski, Tamara; Eggesbø, Merete Åse; Lenters, Virissa; Fernández-Tardón, Guillermo; Subiza-Perez, Mikel; Garcia-Aymerich, Judith; López-Vicente, Mónica; Sunyer, Jordi; Torrent, Maties; Ballester, Ferran; Kelleher, Cecily; Mehegan, John; Berg, Andrea von; Herberth, Gunda; Standl, Marie; Kuehni, Claudia E.; Pedersen, Eva S.L.; Jansen, Maria; Gehring, Ulrike; Boer, Jolanda M.A.; Devereux, Graham; Turner, Steve; Peltola, Ville; Lagström, Hanna; Inskip, Hazel M.; Pike, Katharine C.; Dalmeijer, Geertje W.; Ent, Cornelis K.van der; Thijs, Carel
(2024) BMJ open respiratory research, volume 11, issue 1
(Article)
Abstract
OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study. DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data
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of all cohorts combined. SETTING: Children aged 0-18 years from 26 European birth cohorts. PARTICIPANTS: 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood. MAIN OUTCOME MEASURE: Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6-18 years. RESULTS: Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results. CONCLUSIONS: Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.
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Keywords: Asthma, Exercise, Paediatric asthma, Pulmonary and Respiratory Medicine
ISSN: 2052-4439
Publisher: BMJ Publishing Group
Note: Publisher Copyright: © Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
(Peer reviewed)