Bringing online adaptive radiotherapy to a standard C-arm linac
Groot Koerkamp, Maureen L.; Bol, Gijsbert H.; Kroon, Petra S.; Krikke, Lean L.; Harderwijk, Tessa; Zoetelief, Annelies J.; Scheeren, Annick; van der Vegt, Stefan; Plat, Annika; Hes, Jochem; van Gasteren, Ineke B.A.; Renders, Esmee R.T.; Rutgers, Reijer H.A.; Kok, Saskia W.; van Kaam, Joost; Schimmel-de Kogel, Geja J.; Sikkes, Gonda G.; Winkel, Dennis; van Rijssel, Michael J.; Wopereis, André J.M.; Ishakoglu, Kübra; Noteboom, Juus L.; van der Voort van Zyp, Jochem R.N.; Beck, Naomi; Soeterik, Timo F.W.; van de Pol, Sandrine M.G.; Eppinga, Wietse S.C.; van Es, Corine A.; Raaymakers, Bas W.
(2024) Physics and Imaging in Radiation Oncology, volume 31
(Article)
Abstract
Current online adaptive radiotherapy (oART) workflows require dedicated equipment. Our aim was to develop and implement an oART workflow for a C-arm linac which can be performed using standard clinically available tools. A workflow was successfully developed and implemented. Three patients receiving palliative radiotherapy for bladder cancer were treated, with
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33 of 35 total fractions being delivered with the cone-beam computed tomography (CBCT)-guided oART workflow. Average oART fraction duration was 24 min from start of CBCT acquisition to end of beam on. This work shows how oART could be performed without dedicated equipment, broadening oART availability for application at existing treatment machines.
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Keywords: Bladder cancer, Cone-beam computed tomography, Image-guided radiotherapy, Linear accelerator, Online adaptive radiotherapy (oART), Radiation, Oncology, Radiology Nuclear Medicine and imaging
ISSN: 2405-6316
Publisher: Elsevier
Note: Publisher Copyright: © 2024 The Author(s)
(Peer reviewed)
