Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory

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Comparison of MBT biotargets with MBT steel targets for matrix-assisted laser desorption/ionization time of flight mass spectrometry identifications of microorganisms in a clinical microbiology laboratory
 
Schouten, Robert K P; Schweitzer, Valentijn A; van Marm, Sebastian; Rentenaar, Rob J
(2024) Diagnostic Microbiology and Infectious Disease, volume 109, issue 2
(Article)
Abstract
MALDI-TOF MS identifications of microorganisms in a clinical laboratory were investigated, comparing steel targets with MBT Biotargets. By using MBT Biotargets, the score values of yeast identifications increased, whereas the score values of Gram-negative bacteria decreased. Switching to MBT Biotargets did not negatively impact overall frequencies of high confidence identifications.
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Keywords: Biotarget, Identification, MALDI-TOF MS, Steel target, Yeast, Microbiology (medical), Infectious Diseases
DOI: https://doi.org/10.1016/j.diagmicrobio.2024.116270
ISSN: 0732-8893
Publisher: Elsevier
Note: Publisher Copyright: © 2024 The Author(s)
(Peer reviewed)