Evaluation and Management of Bing-Neel Syndrome

Schep, Sarah J; Vos, Josephine M I; Minnema, Monique C

doi:https://doi.org/10.1016/j.hoc.2023.04.008

Evaluation and Management of Bing-Neel Syndrome

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Evaluation and Management of Bing-Neel Syndrome

Schep, Sarah J; Vos, Josephine M I; Minnema, Monique C

(2023) Hematology/oncology clinics of North America, volume 37, issue 4, pp. 777 - 786

(Article)

Abstract

Bing-Neel syndrome is a rare manifestation of Waldenström macroglobulinemia (WM), which is caused by infiltration of the malignant lymphoplasmacytic cells in the central nervous system. Patients can present with a diverse range of neurologic symptoms, and differentiation with other comorbidities seen in WM, such as immunoglobulin M-related polyneuropathy, can be ... read more

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Keywords: Bing–Neel syndrome, Central nervous system, Cerebrospinal fluid, MRI, Waldenström macroglobulinemia, Hematology, Oncology, Review, Journal Article

DOI: https://doi.org/10.1016/j.hoc.2023.04.008

ISSN: 0889-8588

Publisher: W.B. Saunders Ltd

Note: Funding Information: S.J. Schep: nothing to disclose. M.C. Minnema: Speakers Bureau Janssen-Cilag, WebMD Global, Consultancy Janssen-Cilag, CDR-life, BMS, GSK, research funding; BeiGene; all honoraria are institutional. J.M.I. Vos: consultancy and advisory board (Sanofi), research funding (BeiGene, China & Abbvie, United States/Genmab), Speakers bureau and conference support (BMS); all honoraria are institutional.

(Peer reviewed)