Fibroblast Activation Protein Inhibitor-PET Imaging in Colorectal Cancer

Strating, Esther; van de Loo, Anne; Elias, Sjoerd; Lam, Marnix; Kranenburg, Onno

doi:https://doi.org/10.1016/j.cpet.2023.02.003

Fibroblast Activation Protein Inhibitor-PET Imaging in Colorectal Cancer

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Fibroblast Activation Protein Inhibitor-PET Imaging in Colorectal Cancer

Strating, Esther; van de Loo, Anne; Elias, Sjoerd; Lam, Marnix; Kranenburg, Onno

(2023) PET Clinics, volume 18, issue 3, pp. 325 - 335

(Article)

Abstract

Fibroblast activation protein inhibitor (FAPI)-PET imaging holds great promise for improving the clinical management of colorectal cancer. High fibroblast activation protein expression is particularly observed in lymph node metastases, in the aggressive Consensus Molecular Subtype 4, in peritoneal metastases, and in tumors that respond poorly to immunotherapy. We have defined ... read more

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Keywords: Colorectal cancer, Fibroblast activation protein, Fibroblast activation protein inhibitor, Peritoneal metastases, PET, Radiation, Radiology Nuclear Medicine and imaging, Review, Journal Article

DOI: https://doi.org/10.1016/j.cpet.2023.02.003

ISSN: 1556-8598

Publisher: W.B. Saunders

(Peer reviewed)