Note: Funding Information: GA 101017549 – GENOMED4ALL - H2020-SC1-FA-DTS-2020-1. ‘Genomics and Personalized Medicine for all though Artificial Intelligence in Haematological Diseases’. Instituto de Salud Carlos III through the project ‘PI20/01454: ENABLING PERSONALIZED MEDICINE OF SICKLE CELL DISEASE PATIENTS BASED ON INTEGRATIVE DIAGNOSIS OF NEW GENERATION METHODOLOGIES’ (Co-funded by European Regional Development Fund/European Social Fund; ‘A way to make Europe’/’Investing in your future”). GA 101085717 - ERN-EuroBloodNet – EU4H-2022-ERN-IBA-01 - European Reference Network on Rare hematological diseases – ERN-EuroBloodNet.