ukbpheno v1.0: An R package for phenotyping health-related outcomes in the UK Biobank

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ukbpheno v1.0: An R package for phenotyping health-related outcomes in the UK Biobank
 
Yeung, Ming Wai; van der Harst, Pim; Verweij, Niek
(2022) STAR protocols, volume 3, issue 3
(Article)
Abstract
The complexity and volume of data associated with population-based cohorts means that generating health-related outcomes can be challenging. Using one such cohort, the UK Biobank-a major open access resource-we present a protocol to efficiently integrate the main dataset and record-level data files, to harmonize and process the data using an ... read more
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Keywords: Bioinformatics, Health Sciences, Systems biology, General Biochemistry,Genetics and Molecular Biology, General Immunology and Microbiology, General Neuroscience
DOI: https://doi.org/10.1016/j.xpro.2022.101471
ISSN: 2666-1667
Publisher: Cell Press
Note: Funding Information: This research has been conducted using the UK Biobank resource under application number 74395. We thank all UK Biobank participants for their contributions. M.W.Y. and N.V. conceptualized and developed the ukbpheno package and the protocols. M.W.Y. performed the analyses and wrote the manuscript. N.V. and P.v.d.H. reviewed and edited the manuscript. P.v.d.H. provided the data and project administration. N.V. is a full-time employee of Regeneron Pharmaceutical Inc. and receives stock options and restricted stock units as compensation. Publisher Copyright: © 2022 The Author(s)
(Peer reviewed)