SARS-CoV-2 antibodies persist up to 12 months after natural infection in healthy employees working in non-medical contact-intensive professions

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SARS-CoV-2 antibodies persist up to 12 months after natural infection in healthy employees working in non-medical contact-intensive professions
 
COco study group
(2023) International Journal of Infectious Diseases, volume 126, pp. 155 - 163
(Article)
Abstract
OBJECTIVES: This study aimed to evaluate dynamics of antibody levels after exposure to SARS-CoV-2 for 12 months in Dutch non-vaccinated hairdressers and hospitality staff. METHODS: In this prospective cohort study, blood samples were collected every 3 months for 1 year and analyzed using a qualitative total antibody enzyme-linked immunosorbent assay ... read more
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Keywords: Cohort study, Contact profession, COVID-19 serological testing, Immunoglobulin G, Natural infection, SARS-CoV-2 antibodies, Microbiology (medical), Infectious Diseases, Journal Article
DOI: https://doi.org/10.1016/j.ijid.2022.11.025
ISSN: 1201-9712
Publisher: Elsevier
Note: Funding Information: The COco-study receives financial support from the regional public health service (GGD) of West-Brabant and the Dutch National Institute for Public Health and the Environment (RIVM). These are government-funded, non-commercial organizations, and they did not influence any aspect of the content of the study. Funding Information: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The COco-study receives financial support from the regional public health service (GGD) of West-Brabant and the Dutch National Institute for Public Health and the Environment (RIVM). These are government-funded, non-commercial organizations, and they did not influence any aspect of the content of the study. The COco-study has been approved by the Medical Research Ethics Committees United (MEC-U) at Nieuwegein, The Netherlands (project number A20.247/R20.041). It follows laws and guidelines on research with human subjects, including international standards such as the Declaration of Helsinki. The authors wish to thank all hairdressers and employees in the hospitality industry who voluntarily participated in this study. We would further like to thank the Dutch National Institute for Public Health and the Environment (RIVM) for providing the enzyme-linked immunosorbent assay (ELISA) kits used to measure seroprevalence in our study population and for conducting the quantitative ELISA. We would like to thank the employees of Microvida for conducting the ELISA tests and Anita Blerck, Desiree Bosker, and Karin de Vries at the Regional Public Health Service of West-Brabant (GGD) for contacting participants to ensure participation in questionnaires and scheduling appointments. We would also like to thank Royal Horeca the Netherlands (KHN), and the municipality of Breda for their help with the recruitment of participants. Finally, we would like to thank the management team of the Regional Public Health Service of West-Brabant, in particular Mark van Beers and Fion Brouwer at the RIVM and Ariëne Rietveld, public health physician at the RIVM, and the Regional Public Health Service of Hart voor Brabant, for their support toward and input in this study. Dymphie Mioch: conceptualization, methodology, investigation, formal analysis, writing - original draft. Leonard Vanbrabant: methodology, formal analysis, writing - review & editing. Johan Reimerink: methodology, formal analysis, writing - review & editing. Sandra Kuiper: conceptualization, methodology, formal analysis, writing - review & editing, funding acquisition. Esther Lodder: conceptualization, methodology, formal analysis, writing - review & editing. Wouter van den Bijllaardt: conceptualization, methodology, investigation, formal analysis, writing - review & editing. Jan Kluytmans: conceptualization, methodology, investigation, formal analysis, writing - review & editing. Michel D. Wissing: conceptualization, methodology, investigation, formal analysis, writing - original draft, writing - review & editing, supervision, funding acquisition, visualization. Publisher Copyright: © 2022 The Author(s)
(Peer reviewed)