Pre-hospital treatment with crushed versus integral tablets of prasugrel in patients presenting with ST-Segment Elevation Myocardial Infarction-1-year follow-up results of the COMPARE CRUSH trial: One-year results from the COMPARE CRUSH trial

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Pre-hospital treatment with crushed versus integral tablets of prasugrel in patients presenting with ST-Segment Elevation Myocardial Infarction-1-year follow-up results of the COMPARE CRUSH trial: One-year results from the COMPARE CRUSH trial
 
Vogel, Rosanne F; Delewi, Ronak; Wilschut, Jeroen M; Lemmert, Miguel E; Diletti, Roberto; van Vliet, Ria; van der Waarden, Nancy W P L; Nuis, Rutger-Jan; Paradies, Valeria; Alexopoulos, Dimitrios; Zijlstra, Felix; Montalescot, Gilles; Angiolillo, Dominick J; Krucoff, Mitchell W; Smits, Pieter C; Van Mieghem, Nicolas M; Vlachojannis, Georgios J
(2022) American Heart Journal, volume 252, pp. 26 - 30
(Article)
Abstract
The present research letter reports the 1-year clinical outcomes of the randomized COMPARE CRUSH trial, which allocated STEMI patients at first medical contact in the ambulance to receive either crushed or integral tablets of prasugrel loading dose. This trial aimed to investigate whether early enhanced antiplatelet effect constituted by the ... read more
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Keywords: Cardiology and Cardiovascular Medicine, Letter
DOI: https://doi.org/10.1016/j.ahj.2022.05.022
ISSN: 0002-8703
Publisher: Mosby Inc.
Note: Funding Information: The COMPARE CRUSH trial was funded by grants from MicroPort and Daiichi-Sankyo. The authors are solely responsible for the design and conduct of this study, all study analyses, the drafting and editing of the paper and its final contents. Funding Information: The COMPARE CRUSH trial was funded by Maasstad research B.V. (Rotterdam, the Netherlands), which received unrestricted grants from Daiichi-Sankyo (grant number 039-20170327-EFI ) and Shanghai MicroPort Medical (grant number MPSH20170801148570110945). The funding companies were not involved in the conduct of the trial, the analysis of the data, or the drafts of the manuscripts. Publisher Copyright: © 2022 Elsevier Inc.
(Peer reviewed)