Respiratory Pathogen Detection in Children: Saliva as a Diagnostic Specimen

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Respiratory Pathogen Detection in Children: Saliva as a Diagnostic Specimen
 
De Koff, Emma M.; Euser, Sjoerd M.; Badoux, Paul; Sluiter-Post, Judith; Eggink, Dirk; Sanders, Elisabeth A.M.; Van Houten, Marlies A.
(2021) Pediatric Infectious Disease Journal, volume 40, issue 9, pp. E351 - E353
(Article)
Abstract
We compared pathogen detection between saliva, nasopharyngeal and oropharyngeal swabs in children with respiratory symptoms. The sensitivity in nasopharyngeal swabs was 93% (95% confidence interval [CI]: 78%-98%), in oropharyngeal swabs 79% (95% CI: 60%-90%), in saliva overall 76% (95% CI: 58%-88%) and in 18 saliva samples collected with drooling or ... read more
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Keywords: diagnostics, pediatrics, respiratory pathogens, saliva, Pediatrics, Perinatology, and Child Health, Microbiology (medical), Infectious Diseases
DOI: https://doi.org/10.1097/INF.0000000000003191
ISSN: 0891-3668
Publisher: Lippincott Williams and Wilkins
Note: Funding Information: M.A.v.H. has received grants from Pfizer unrelated to this work. The other authors have no conflicts of interest to disclose. Funding Information: This work was funded by the Spaarne Gasthuis Hoofddorp and Haarlem and the Regional Public Health Laboratory Kennemerland Haarlem. No external funding was received. Publisher Copyright: © 2021 Lippincott Williams and Wilkins. All rights reserved.
(Peer reviewed)