Note: Funding Information: This study is supported by Fondazione Cariverona: Oncology Biobank Project ?Antonio Schiavi? (prot. 203885/2017), Fondazione Italiana Malattie Pancreas (FIMP-Ministero Salute J38D19000690001), Italian Ministry of Health (RF CO-2019-12369662: CUP: B39C21000370001), and by the Dutch Cancer Society [KWF grant 2016 10289].