Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements

Muller, Steven A.; Leavis, Helen L.; Taha, Karim; Koenderman, Leo; Chamuleau, Steven A.J.; Suyker, Willem J.L.; Cramer, Maarten J.

doi:https://doi.org/10.1016/j.jaccas.2021.07.034

Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements

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Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements

Muller, Steven A.; Leavis, Helen L.; Taha, Karim; Koenderman, Leo; Chamuleau, Steven A.J.; Suyker, Willem J.L.; Cramer, Maarten J.

(2021) JACC Case Rep, volume 3, issue 13, pp. 1483 - 1488

(Article)

Abstract

We present a young patient who had to undergo 5 mitral valve replacements (MVR) because of a repetitive immune-mediated noninfectious endocarditis. The patient was treated with multiple anti-inflammatory drugs and high-dose prednisone. After the fifth MVR, the patient remained in stable condition using Anakinra after 22 months of follow-up. (Level ... read more

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Keywords: Anakinra, autoimmune, endocarditis, mitral valve replacement, repetitive, Cardiology and Cardiovascular Medicine, Case Reports

DOI: https://doi.org/10.1016/j.jaccas.2021.07.034

ISSN: 2666-0849

Publisher: Elsevier

(Peer reviewed)