Note: Funding Information: JT has participated in research projects funded by grants from Janssen-Cilag and Eli Lilly, reports personal fees from the Finnish Medicines Agency, European Medicines Agency, Eli Lilly, Janssen-Cilag, Lundbeck, and Otsuka, grants from the Stanley Foundation and Sigrid Jusélius Foundation, and is a member of the advisory board for Lundbeck. JJL declares no competing interests.