Initial Clinical Experience of MR-Guided Radiotherapy for Non-Small Cell Lung Cancer
Crockett, Cathryn B; Samson, Pamela; Chuter, Robert; Dubec, Michael; Faivre-Finn, Corinne; Green, Olga L; Hackett, Sara L; McDonald, Fiona; Robinson, Clifford; Shiarli, Anna-Maria; Straza, Michael W; Verhoeff, Joost J C; Werner-Wasik, Maria; Vlacich, Gregory; Cobben, David
(2021) Frontiers in oncology, volume 11, pp.
(Article)
Abstract
Curative-intent radiotherapy plays an integral role in the treatment of lung cancer and therefore improving its therapeutic index is vital. MR guided radiotherapy (MRgRT) systems are the latest technological advance which may help with achieving this aim. The majority of MRgRT treatments delivered to date have been stereotactic body radiation
... read more
therapy (SBRT) based and include the treatment of (ultra-) central tumors. However, there is a move to also implement MRgRT as curative-intent treatment for patients with inoperable locally advanced NSCLC. This paper presents the initial clinical experience of using the two commercially available systems to date: the ViewRay MRIdian and Elekta Unity. The challenges and potential solutions associated with MRgRT in lung cancer will also be highlighted.
show less
Download/Full Text
Keywords: adaptive, external beam radiotherapy, image-guided radiotherapy (IGRT), magnetic resonance imaging (MRI), MR-guided radiotherapy (MRgRT), non-small cell lung cancer (NSCLC), stereotactic body radiation therapy (SBRT), Oncology, Cancer Research, Journal Article
ISSN: 2234-943X
Publisher: Frontiers Media S. A.
Note: Funding Information: Part of the publication fee has been funded by NIHR Manchester Biomedical Research Centre (Award number: BRC-1215-20007). Publisher Copyright: © Copyright © 2021 Crockett, Samson, Chuter, Dubec, Faivre-Finn, Green, Hackett, McDonald, Robinson, Shiarli, Straza, Verhoeff, Werner-Wasik, Vlacich and Cobben. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
(Peer reviewed)
