Note: Funding Information: C.D.C.C.v.d.H., E.M.M.S., E.H.J.G.A., M.W have nothing to declare. N.P.R. received funding from the European Union Horizon 2020 research and innovation program REPROGRAM under grant agreement No 667837, and received an IN-CONTROL CVON grant from the Dutch Heart Foundation (CVON2012-03 and CVON2018-27). N.P.R. is recipient of a grant of the ERA-CVD Joint Transnational Call 2018, which is supported by the Dutch Heart Foundation (JTC2018, project MEMORY); 2018T093). S.C.A.d.J. was supported by the Dutch Heart Foundation (CVON2014-11 RECONNECT) and Queen of Hearts Program 2013T084.