Note: Funding Information: The authors acknowledge funding from the Cancer Research UK Glasgow Centre (A25142 to SBC), the Wellcome Trust (208990/ Z/17/Z to SBC), the Medical Research Council (MR/R502327/1 to SBC), Breast Cancer Now (2018JulPR1101 and 2019DecPhD1349 to SBC), Tenovus Scotland (S17-17 to SBC), the Deutsche Forschungsgemeinschaft (Ka 502/19-2 to DK), the Wilhelm Sander Foundation (2018.045.1 to DK), “la Caixa” Banking Foundation (HR18-00069 to BS-S), the Dutch Research Council (NWO ZonMW 43400003 to JK), the Dutch Cancer Society (KWF UU 2014-6790, UU 2015-7601, UU 2018-11393, UU 2018-11979, UU 2019-12586, UU 2020-13043 to JK). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.