Characteristics and outcome of children with renal cell carcinoma: A narrative review
van der Beek, Justine N.; Geller, James I.; de Krijger, Ronald R.; Graf, Norbert; Pritchard-Jones, Kathy; Drost, Jarno; Verschuur, Arnauld C.; Murphy, Dermot; Ray, Satyajit; Spreafico, Filippo; Dzhuma, Kristina; Littooij, Annemieke S.; Selle, Barbara; Tytgat, Godelieve A.M.; van den Heuvel-Eibrink, Marry M.
(2020) Cancers, volume 12, issue 7, pp. 1 - 26
(Article)
Abstract
Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequently occurring adult types of RCC.
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However, published pediatric data suggest that clinical, molecular and histological characteristics of pediatric RCC differ from adult RCC. This paper summarizes reported series consisting of ≥10 RCC pediatric patients in order to create an up-to-date overview of the clinical and histopathological characteristics, treatment and outcome of pediatric RCC patients.
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Keywords: Outcome, Pediatric, Renal cell carcinoma, Survival, Treatment, treatment, renal cell carcinoma, survival, outcome, pediatric, Oncology, Cancer Research, Review, Journal Article
ISSN: 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
Note: Funding Information: This research was supported by a grant (nr. 341) from the Kika (Children Cancer-Free) Foundation. Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
(Peer reviewed)
