The incidence of psychotic disorders among migrants and minority ethnic groups in Europe: findings from the multinational EU-GEI study
Termorshuizen, Fabian; van der Ven, Els; Tarricone, Ilaria; Jongsma, Hannah E; Gayer-Anderson, Charlotte; Lasalvia, Antonio; Tosato, Sarah; Quattrone, Diego; La Cascia, Caterina; Szöke, Andrei; Berardi, Domenico; Llorca, Pierre-Michel; de Haan, Lieuwe; Velthorst, Eva; Bernardo, Miguel; Sanjuán, Julio; Arrojo, Manuel; Murray, Robin M; Rutten, Bart P; Jones, Peter B; van Os, Jim; Kirkbride, James B; Morgan, Craig; Selten, Jean-Paul
(2022) Psychological medicine, volume 52, issue 7, pp. 1376 - 1385
(Article)
Abstract
BACKGROUND: In Europe, the incidence of psychotic disorder is high in certain migrant and minority ethnic groups (hence: 'minorities'). However, it is unknown how the incidence pattern for these groups varies within this continent. Our objective was to compare, across sites in France, Italy, Spain, the UK and the Netherlands,
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the incidence rates for minorities and the incidence rate ratios (IRRs, minorities v. the local reference population). METHODS: The European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI) study was conducted between 2010 and 2015. We analyzed data on incident cases of non-organic psychosis (International Classification of Diseases, 10th edition, codes F20-F33) from 13 sites. RESULTS: The standardized incidence rates for minorities, combined into one category, varied from 12.2 in Valencia to 82.5 per 100 000 in Paris. These rates were generally high at sites with high rates for the reference population, and low at sites with low rates for the reference population. IRRs for minorities (combined into one category) varied from 0.70 (95% CI 0.32-1.53) in Valencia to 2.47 (95% CI 1.66-3.69) in Paris (test for interaction: p = 0.031). At most sites, IRRs were higher for persons from non-Western countries than for those from Western countries, with the highest IRRs for individuals from sub-Saharan Africa (adjusted IRR = 3.23, 95% CI 2.66-3.93). CONCLUSIONS: Incidence rates vary by region of origin, region of destination and their combination. This suggests that they are strongly influenced by the social context.
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Keywords: Dopamine, epidemiology, ethnicity, migration, psychosis, race, schizophrenia, stress, Psychiatry and Mental health, Applied Psychology, Journal Article
ISSN: 0033-2917
Publisher: Cambridge University Press
Note: Funding Information: The EU-GEI Project is funded by grant agreement HEALTH-F2-2010-241909 (Project EU-GEI) from the European Community's Seventh Framework Programme. The Brazilian study was funded by grant 2012/0417-0. Publisher Copyright: © The Author(s), 2020. Published by Cambridge University Press.
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