Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren's syndrome is associated with B cell hyperactivity and type I interferon activity

Note: Funding Information: Contributors MRH, KU, EK, AvM, JAGvR and TRDJR made substantial contributions to conception and design. MH, KU, SB, and TS were involved in sample collection. MRH, KU, and AP performed data analysis. MRH and KU drafted the paper. All authors were involved in data interpretation and revision of the paper for important intellectual content. All authors approved the final manuscript. Funding This work was in part funded by GlaxoSmithKline. MH was supported by the Dutch Arthritis Society (ReumaNederland, grant nr 17-2-301). Competing interests TR is a principal investigator in the Immunology Catalyst programme at GlaxoSmithKline, which is an independent research programme. He did not receive any financial support other than the research funding for the current project. The other authors have declared no conflicts of interest. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.