Abstract
Therapeutic peptides/proteins and protein-based antigens are chemically and structurally labile compounds,
which are almost exclusively administered by parenteral injections. Recently, non-invasive mucosal routes
have attracted interest for administration of these biotherapeutics. Chitosan-based delivery systems enhance
the absorption and/or cellular uptake of peptides/proteins across mucosal sites and have immunoadjuvant
properties. Chitosan is a mucoadhesive polysaccharide
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