Note: Funding Information: This work was supported by the European Union's Horizon 2020 Research and Innovation Program under grant agreement No 683356 - FOLSMART (AO-R and HS). We would like to thank all the authors who have participated in this Research Topic, the reviewers for their invaluable comments and the Frontiers staff for their assistance. Funding Information: This work was supported by the European Union’s Horizon 2020 Research and Innovation Program under grant agreement No 683356 - FOLSMART (AO-R and HS).