Abstract
Organic anion transporting polypeptide 2B1 (OATP2B1/SLCO2B1) facilitates uptake transport of structurally diverse endogenous and exogenous compounds. To investigate the roles of OATP2B1 in physiology and pharmacology, we established and characterized Oatp2b1 knockout (single Slco2b1 -/- and combination Slco1a/1b/2b1 -/-) and humanized hepatic and intestinal OATP2B1 transgenic mouse models. While viable
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