Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain
Rodon, Jordi; Mykytyn, Anna Z; Te, Nigeer; Okba, Nisreen M A; Lamers, Mart M; Pailler-García, Lola; Cantero, Guillermo; Albulescu, Irina; Bosch, Berend-Jan; Peiris, Malik; Bensaid, Albert; Vergara-Alert, Júlia; Haagmans, Bart L; Segalés, Joaquim
(2023) Emerging Infectious Diseases, volume 29, issue 3, pp. 585 - 589
(Article)
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) clade B viruses are found in camelids and humans in the Middle East, but clade C viruses are not. We provide experimental evidence for extended shedding of MERS-CoV clade B viruses in llamas, which might explain why they outcompete clade C strains in the
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Arabian Peninsula.
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Keywords: Animals, Humans, Middle East Respiratory Syndrome Coronavirus, Camelids, New World, Herpesvirus 1, Cercopithecine, Coronavirus Infections, Virus Shedding, Camelus, Dromedary camels, Respiratory syndrome coronavirus, Microbiology (medical), Infectious Diseases, Epidemiology
ISSN: 1080-6040
Publisher: Centers for Disease Control and Prevention (CDC)
Note: Funding Information: This study was performed as part of the Zoonotic Anticipation and Preparedness Initiative (ZAPI project) (Innovative Medicines initiative [IMI] grant 115760), with assistance and financial support from IMI and the European Commission and contributions from EFPIA partners. J.R. was partially supported by the VetBioNet project (EU Grant Agreement INFRA-2016-1 Nº731014) and the crowdfunding initiative #Yomecorono, available online at https://www.yomecorono.com (accessed on June 16, 2022). IRTA is supported by CERCA Programme/ Generalitat de Catalunya. Publisher Copyright: © 2023 Centers for Disease Control and Prevention (CDC). All rights reserved.
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