Detailed analysis of the D-galactose catabolic pathways in Aspergillus niger reveals complexity at both metabolic and regulatory level

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Detailed analysis of the D-galactose catabolic pathways in Aspergillus niger reveals complexity at both metabolic and regulatory level
 
Chroumpi, Tania; Martínez-Reyes, Natalia; Kun, Roland S.; Peng, Mao; Lipzen, Anna; Ng, Vivian; Tejomurthula, Sravanthi; Zhang, Yu; Grigoriev, Igor V.; Mäkelä, Miia R.; de Vries, Ronald P.; Garrigues, Sandra
(2022) Fungal Genetics and Biology, volume 159
(Article)
Abstract
The current impetus towards a sustainable bio-based economy has accelerated research to better understand the mechanisms through which filamentous fungi convert plant biomass, a valuable feedstock for biotechnological applications. Several transcription factors have been reported to control the polysaccharide degradation and metabolism of the resulting sugars in fungi. However, little ... read more
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Keywords: Aspergillus niger, D-galactose catabolism, Leloir pathway, Oxido-reductive D-galactose catabolic pathway, Pentose Catabolic Pathway (PCP), Transcription factors, Microbiology, Genetics
DOI: https://doi.org/10.1016/j.fgb.2022.103670
ISSN: 1087-1845
Publisher: Academic Press Inc.
Note: Funding Information: TC was supported by a grant of the NWO ALWOP.233 to RPdV. RSK and SG were supported by a grant of the Applied Science division (TTW) of NWO and the Technology Program of the Ministry of Infrastructure and Water Management 15807 to RPdV. The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, was supported by the Office of Science of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. The Academy of Finland grant no. 308284 to MRM is also acknowledged. Publisher Copyright: © 2022 The Author(s)
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