Abstract
The neurotrophic and neuroprotective potential of the -melanocyte-stimulating hormone (-MSH) analog cyclo-[Ac-Nle4,Asp5,-Phe7,Lys10]-MSH-(410) amide (melanotan-II), a potent melanocortin receptor agonist, was investigated. The sciatic nerve crush model was used as a paradigm to investigate the neurotrophic properties of melanotan-II. Melanotan-II significantly enhanced the recovery of sensory function following a crush lesion
... read more