Micro cell vesicle technology (mCVT): a novel hybrid system of gene delivery for hard-to-transfect (HTT) cells

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Micro cell vesicle technology (mCVT): a novel hybrid system of gene delivery for hard-to-transfect (HTT) cells
 
Ou, Yi-Hsuan; Zou, Shui; Goh, Wei Jiang; Chong, Suet Yen; Venkatesan, Gopalakrishnan; Wacker, Matthias G; Storm, Gerrit; Wang, Jiong-Wei; Czarny, Bertrand; Pastorin, Giorgia; Woon, Esther C Y
(2020) Nanoscale, volume 12, issue 35, pp. 18022 - 18030
(Article)
Abstract
A hybrid gene delivery platform, micro Cell Vesicle Technology (mCVT), produced from the fusion of plasma membranes and cationic lipids, is presently used to improve the transfection efficiency of hard-to-transfect (HTT) cells. The plasma membrane components of mCVTs impart specificity in cellular uptake and reduce cytotoxicity in the transfection process, ... read more
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Open Access version via Utrecht University Repository Publisher version
 
Keywords: Taverne
DOI: https://doi.org/10.1039/d0nr03784b
ISSN: 2040-3364
Publisher: Royal Society of Chemistry
(Peer reviewed)
 
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