Note: Funding Information: M.D.P. is employed by the Victorian Clinical Genetics Services (VCGS), which is a not-for-profit provider of gw-cfDNA screening tests and derives income from these tests. VCGS has previously received funding from Illumina Inc. for a gw-cfDNA screening clinical study. M.P.D. declares no personal conflict of interest. The other authors declare no conflicts of interest. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.