Well-differentiated Neuroendocrine Carcinoma of the Larynx: Confusion of Terminology and Uncertainty of Early Studies
Hunt, Jennifer L; Barnes, Leon; Triantafyllou, Asterios; Gnepp, Douglas R; Devaney, Kenneth O; Stenman, Göran; Halmos, Gyorgy B; Bishop, Justin A; Skálová, Alena; Willems, Stefan M; Hellquist, Henrik; Rinaldo, Alessandra; Ferlito, Alfio
(2019) Advances in anatomic pathology, volume 26, issue 4, pp. 246 - 250
(Article)
Abstract
Well-differentiated neuroendocrine carcinoma (also known as "carcinoid") of the larynx is an exceedingly rare tumor that has an epithelial origin. These tumors are malignant and have a low, but definite, risk of metastasis. Although it can be challenging, this tumor should be differentiated from moderately differentiated neuroendocrine carcinoma (also known
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as "atypical carcinoid"). The clinical and pathologic features of this tumor, as well as treatment and prognosis, are reviewed in detail.
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Keywords: atypical carcinoid, carcinoid, large cell neuroendocrine carcinoma, larynx, small cell neuroendocrine carcinoma, well-differentiated neuroendocrine carcinoma, Uncertainty, Humans, Neuroendocrine Tumors/diagnosis, Laryngeal Neoplasms/diagnosis, Carcinoid Tumor/diagnosis, Larynx/pathology, Carcinoma, Neuroendocrine/diagnosis, Anatomy, Pathology and Forensic Medicine, Journal Article, Review
ISSN: 1072-4109
Publisher: Lippincott Williams and Wilkins
(Peer reviewed)