Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: feasibility in the porcine heart

Abstract

The MIGRATE (MrI Guided RegenerAtive ThErapy) consortium is a combined scientific and industrial effort to establish an MRIguided intramyocardial injection platform. By collaborating within the MIGRATE consortium we were able to combine state-of-theart interventional imaging hardware, software, MRI-compatible catheters, and biomaterials. In this pilot study, we demonstrated the feasibility of intramyocardial injections of an MRI-visible biomaterial by interventional MRI using a combination of active tracking and passive visualisation.