Abstract
Background: Natural killer T (NKT)cells in adipose tissue (AT)contribute to whole body energy homeostasis. Results: Inhibition of the glucosylceramide synthesis in adipocytes impairs iNKT cell activity. Conclusion: Glucosylceramide biosynthesis pathway is important for endogenous lipid antigen activation of iNKT cells in adipocytes. Significance: Unraveling adipocyte-iNKT cell communication may help to
... read more