Tyrosine kinase inhibitor levels matter in treating chronic GVHD

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Tyrosine kinase inhibitor levels matter in treating chronic GVHD
 
van der Wagen, Lotte; Janssen, Julie; Raijmakers, Reinier; Petersen, Eefke; de Witte, Moniek; de Jong, Niels; Bellido, Mar; Meijer, Ellen; Bär, Brigitte; Jan Boelens, Jaap; Huitema, Alwin; Kuball, Jürgen
(2019) Bone Marrow Transplantation, volume 54, issue 7, pp. 1141 - 1144
(Comment)
Abstract
We observed a possible concentration effect relationship for nilotinib on resolution of chronic Graft versus Host disease.These data suggest therapeutic drug monitoring might be useful for patients receiving tyrosine kinase inhibitors for chronic GVHD.
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Keywords: Hematology, Transplantation
DOI: https://doi.org/10.1038/s41409-018-0429-5
ISSN: 0268-3369
Publisher: Nature Publishing Group
(Peer reviewed)