Adaptive designs in clinical trials in critically ill patients: principles, advantages and pitfalls

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Adaptive designs in clinical trials in critically ill patients: principles, advantages and pitfalls
 
van Werkhoven, C H; Harbarth, S; Bonten, M J M
(2019) Intensive Care Medicine, volume 45, issue 5, pp. 678 - 682
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Keywords: Critical Care and Intensive Care Medicine
DOI: https://doi.org/10.1007/s00134-018-5426-z
ISSN: 0342-4642
Publisher: Springer Verlag
Note: Funding Information: This work was supported by the Innovative Medicines Initiative Joint Undertaking (IMI JU) (Grant number 115523), Combatting Bacterial Resistance in Europe (COMBACTE), resources of which are composed of financial contribution from the European Union?s 7th Framework Programme (FP7/2007???2013) and the European Federation of Pharmaceutical Industries and Associations (EFPIA) companies? in kind contribution. Funding Information: This work was supported by the Innovative Medicines Initiative Joint Undertaking (IMI JU) (Grant number 115523), Combatting Bacterial
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