Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren's syndrome: mTOR inhibition as a novel therapeutic strategy to halt immunopathology?

Blokland, Sofie L M; Hillen, Maarten R; Wichers, Catharina G K; Zimmermann, Maili; Kruize, Aike A; Radstake, Timothy R D J; Broen, Jasper C A; van Roon, Joel A G

doi:https://doi.org/10.1136/rmdopen-2018-000701

Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren's syndrome: mTOR inhibition as a novel therapeutic strategy to halt immunopathology?

DSpace/Manakin Repository

Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren's syndrome: mTOR inhibition as a novel therapeutic strategy to halt immunopathology?

Blokland, Sofie L M; Hillen, Maarten R; Wichers, Catharina G K; Zimmermann, Maili; Kruize, Aike A; Radstake, Timothy R D J; Broen, Jasper C A; van Roon, Joel A G

(2019) RMD Open, volume 5, issue 1

(Article)

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Keywords: B cells, Sjögren's syndrome, T cells, mTOR, rapamycin, Immunology and Allergy, Rheumatology, Immunology

DOI: https://doi.org/10.1136/rmdopen-2018-000701

ISSN: 2056-5933

Publisher: BMJ Publishing Group

(Peer reviewed)