Abstract
The human macrophage galactose-type lectin (MGL) is a C-type lectin characterized by a unique specificity for terminal N-acetylgalactosamine residues present in the tumor-associated Tn antigen (αGalNAc-Ser/Thr) and its sialylated form, the sialyl-Tn antigen. However, human MGL has multiple splice variants, and whether these variants have distinct ligand-binding properties is unknown.
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