Abstract
Expression of the transcription factor SOX4 is often elevated in human cancers, where it generally correlates with tumor-progression and poor-disease outcome. Reduction of SOX4 expression results in both diminished tumor-incidence and metastasis. In breast cancer, TGF--mediated induction of SOX4 has been shown to contribute to epithelial-to-mesenchymal transition (EMT), which controls
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