Pharmaceutics of oral anticancer agents and stimulants

Abstract

In summary, this thesis shows the current situation of highly specific anticancer agents of which the clinical performance is significantly hindered by a low and variable bioavailability. In addition, it clearly shows that by way of a well-designed formulation, this clinical performance can be greatly improved. Furthermore, the research clearly shows the desired pharmacokinetics of sustained-release dexamphetamine at two dose levels. It provides further evidence in favor of the implementation of SR dexamphetamine in the therapy of cocaine dependence.