Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): Results from the burden of communicable diseases in Europe study, European Union and European economic countries, 2009 to 2013
Cassini, Alessandro; Colzani, Edoardo; Pini, Alessandro; Mangen, Marie Josee J.; Plass, Dietrich; McDonald, Scott A.; Maringhini, Guido; van Lier, Alies; Haagsma, Juanita A.; Havelaar, Arie H.; Kramarz, Piotr; Kretzschmar, Mirjam E.; BCoDE consortium
(2018) Eurosurveillance, volume 23, issue 16, pp. 15 - 34
(Article)
Abstract
Background and aims: The Burden of Communicable Diseases in Europe (BCoDE) study aimed to calculate disability-adjusted life years (DALYs) for 31 selected diseases in the European Union (EU) and European Economic Area (EEA). Methods: DALYs were estimated using an incidence-based and pathogen-based approach. Incidence was estimated through assessment of data
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availability and quality, and a correction was applied for under-estimation. Calculation of DALYs was performed with the BCoDE software toolkit without applying time discounting and age-weighting. Results: We estimated that one in 14 inhabitants experienced an infectious disease episode for a total burden of 1.38 million DALYs (95% uncertainty interval (UI): 1.25-1.5) between 2009 and 2013; 76% of which was related to the acute phase of the infection and its short-term complications. Influenza had the highest burden (30% of the total burden), followed by tuberculosis, human immunodeficiency virus (HIV) infection/AIDS and invasive pneumococcal disease (IPD). Men had the highest burden measured in DALYs (60% of the total), adults 65 years of age and over had 24% and children less than 5 years of age had 11%. Age groupspecific burden showed that infants (less than 1 year of age) and elderly people (80 years of age and over) experienced the highest burden. Conclusions: These results provide baseline estimates for evaluating infectious disease prevention and control strategies. The study promotes an evidence-based approach to describing population health and assessing surveillance data availability and quality, and provides information for the planning and prioritisation of limited resources in infectious disease prevention and control.
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Keywords: Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Communicable Diseases/epidemiology, Cost of Illness, Disabled Persons/statistics & numerical data, Europe/epidemiology, European Union/statistics & numerical data, Female, Humans, Incidence, Infant, Life Expectancy, Male, Models, Statistical, Population Health, Quality-Adjusted Life Years, Journal Article, Research Support, Non-U.S. Gov't
ISSN: 1025-496X
Publisher: Centre Europeen pour la Surveillance Epidemiologique du SIDA
Note: Funding Information: In 2006, the European Centre for Disease Prevention and Control (ECDC) commissioned a pilot disease burden study using seven selected infectious diseases in order to propose a methodology for a burden of disease study tailored towards infectious diseases and assess the feasibility of, and interest in, such an approach [17]. Based on this pilot, the Burden of Communicable Diseases in Europe (BCoDE) project was launched [18], funded by ECDC and implemented in collaboration with a European consortium led by the Dutch National Institute for Public Health and the Environment (RIVM) and consisting of academic and national health institutes from EU countries. Publisher Copyright: © 2018, European Centre for Disease Prevention and Control (ECDC). All rights reserved.
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