Note: Funding Information: We thank Ms. Daniëlle S. van Rossum (UMC Utrecht, Utrecht, The Netherlands) for stimulating discussions. Work on non-coding RNAin the lab is financially supported by FP7-HEALTH-2013-INNOVATION-1, Collaborative project Epi-miRNA, the Marie Curie ETN“circRTrain,” and Epilepsiefonds (12-08, 15-05) (to RP). Funding Information: We thank Ms. Daniëlle S. van Rossum (UMC Utrecht, Utrecht, The Netherlands) for stimulating discussions. Work on noncoding RNA in the lab is financially supported by FP7-HEALTH-2013-INNOVATION-1, Collaborative project Epi-miRNA, the Marie Curie ETN “circRTrain,” and Epilepsiefonds (12-08, 15-05) (to RP).