Endorectal Brachytherapy Boost After External Beam Radiation Therapy in Elderly or Medically Inoperable Patients With Rectal Cancer: Primary Outcomes of the Phase 1 HERBERT Study

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Endorectal Brachytherapy Boost After External Beam Radiation Therapy in Elderly or Medically Inoperable Patients With Rectal Cancer: Primary Outcomes of the Phase 1 HERBERT Study
 
Rijkmans, Eva C.; Cats, Annemieke; Nout, Remi A.; van den Bongard, Desiree; Ketelaars, Martijn; Buijsen, Jeroen; Rozema, Tom; Franssen, Jan Huib; Velema, Laura A.; van Triest, Baukelien; Marijnen, Corrie A M
(2017) International Journal of Radiation Oncology Biology Physics, volume 98, issue 4, pp. 908 - 917
(Article)
Abstract
Purpose: To evaluate the toxicity and efficacy of the combination of external beam radiation therapy (EBRT) followed by high-dose-rate endorectal brachytherapy (HDREBT) boost in elderly and medically inoperable patients with rectal cancer. Methods and Materials: A phase 1 dose-escalation study was performed. Treatment consisted of EBRT (13 × 3 Gy) ... read more
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Keywords: Radiation, Oncology, Radiology Nuclear Medicine and imaging, Cancer Research, Journal Article, Clinical Trial, Phase I
DOI: https://doi.org/10.1016/j.ijrobp.2017.01.033
ISSN: 0360-3016
Publisher: Elsevier Inc.
(Peer reviewed)