Endometrial cancer risk prediction including serum-based biomarkers: results from the EPIC cohort

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Endometrial cancer risk prediction including serum-based biomarkers: results from the EPIC cohort
 
Fortner, Renée T.; Hüsing, Anika; Kühn, Tilman; Konar, Meric; Overvad, Kim; Tjønneland, Anne; Hansen, Louise; Boutron-Ruault, Marie Christine; Severi, Gianluca; Fournier, Agnès; Boeing, Heiner; Trichopoulou, Antonia; Benetou, Vasiliki; Orfanos, Philippos; Masala, Giovanna; Agnoli, Claudia; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, H. Bas; Peeters, Petra H M; Weiderpass, Elisabete; Gram, Inger T.; Gavrilyuk, Oxana; Quirós, J. Ramón; Maria Huerta, José; Ardanaz, Eva; Larrañaga, Nerea; Lujan-Barroso, Leila; Sánchez-Cantalejo, Emilio; Butt, Salma Tunå; Borgquist, Signe; Idahl, Annika; Lundin, Eva; Khaw, Kay Tee; Allen, Naomi E.; Rinaldi, Sabina; Dossus, Laure; Gunter, Marc; Merritt, Melissa A.; Tzoulaki, Ioanna; Riboli, Elio; Kaaks, Rudolf
(2017) International Journal of Cancer, volume 140, issue 6, pp. 1317 - 1323
(Article)
Abstract
Endometrial cancer risk prediction models including lifestyle, anthropometric and reproductive factors have limited discrimination. Adding biomarker data to these models may improve predictive capacity; to our knowledge, this has not been investigated for endometrial cancer. Using a nested case–control study within the European Prospective Investigation into Cancer and Nutrition (EPIC) ... read more
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Keywords: adipokines, cytokines, endometrial cancer, growth factors, inflammatory markers, lipids, metabolic markers, prospective cohort, risk prediction, sex steroids, General Medicine, Oncology, Cancer Research, Journal Article, Multicenter Study
DOI: https://doi.org/10.1002/ijc.30560
ISSN: 0020-7136
Publisher: John Wiley & Sons Inc.
Note: Funding Information: RT Fortner was supported by a Marie Curie International Incoming Fellowship of the European Commission's Seventh Framework Programme (MC-IIF-623984). For information on how to submit an application for gaining access to EPIC data and/or biospecimens, please follow the instructions at http://epic.iarc.fr/access/index.php. Publisher Copyright: © 2016 UICC
(Peer reviewed)