Intramyocardial stem cell injection: go(ne) with the flow

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Intramyocardial stem cell injection: go(ne) with the flow
 
van den Akker, Frederieke; Feyen, Dries A M; van den Hoogen, Patricia; van Laake, Linda W; van Eeuwijk, Esther C M; Hoefer, Imo; Pasterkamp, Gerard; Chamuleau, Steven A J; Grundeman, Paul F; Doevendans, Pieter A; Sluijter, Joost P G
(2017) European Heart Journal, volume 38, issue 3, pp. 184 - 186
(Article)
Abstract
In this study, we visualize the real-time dynamics of intramyocardial stem-cell injections. This shows a massive, immediate wash-out via venous drainage, accounting for the low retention. The use of carriers reduces this outflow.
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Keywords: Stem cell therapy, Intracardiac injections, Venous drainage, Journal Article
DOI: https://doi.org/10.1093/eurheartj/ehw056
ISSN: 0195-668X
Publisher: Oxford University Press
(Peer reviewed)