Lung Cancer Among Firefighters: Smoking-Adjusted Risk Estimates in a Pooled Analysis of Case-Control Studies
Bigert, C; Gustavsson, P; Straif, K; Taeger, D; Pesch, B; Kendzia, B; Schuz, J; Stucker, I; Guida, F; Bruske, I; Wichmann, H E; Pesatori, A C; Landi, M T; Caporaso, N; Tse, L A; Yu, I T; Siemiatycki, J; Lavoue, J; Richiardi, L; Mirabelli, D; Simonato, L; Jockel, K H; Ahrens, W; Pohlabeln, H; Tardon, A; Zaridze, D; Field, J K; t Mannetje, A; Pearce, N; McLaughlin, J; Demers, P; Szeszenia-Dabrowska, N; Lissowska, J; Rudnai, P; Fabianova, E; Stanescu Dumitru, R; Bencko, V; Foretova, L; Janout, V; Boffetta, P; Peters, S; Vermeulen, R; Kromhout, H; Bruning, T; Olsson, A C
(2016) International Journal of Occupational and Environmental Health, volume 58, issue 11, pp. 1137 - 1143
(Article)
Abstract
OBJECTIVES: The aim of this study was to explore lung cancer risk among firefighters, with adjustment for smoking. METHODS: We used pooled information from the SYNERGY project including 14 case-control studies conducted in Europe, Canada, New Zealand, and China, with lifetime work histories and smoking habits for 14,748 cases of
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lung cancer and 17,543 controls. We estimated odds ratios by unconditional logistic regression with adjustment for smoking and having ever been employed in a job known to present an excess risk of lung cancer. RESULTS: There was no increased lung cancer risk overall or by specific cell type among firefighters (n = 190), neither before nor after smoking adjustment. We observed no significant exposure-response relationship in terms of work duration. CONCLUSIONS: We found no evidence of an excess lung cancer risk related to occupational exposure as a firefighter.
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Keywords: Taverne
ISSN: 1077-3525
Publisher: Maney Publishing
(Peer reviewed)