Bruker matrix-assisted laser desorption/ionization time-of-flight mass spectrometry identification of Neisseria gonorrhoeae is improved by a database extension

Abstract

Bruker MALDI-TOF MS identification of Neisseria gonorrhoeae may be affected by "B consistency categorization". A supplementary database of 17 N. gonorrhoeae main spectra was constructed. 12/64 N. gonorrhoeae identifications were categorized with B consistency, which disappeared using the supplementary database. Database extension did not result in misidentification of Neisseria meningitidis.