Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma

Sparidans, Rolf W; Rosing, Hilde; Rood, Johannes J M; Schellens, Jan H M; Beijnen, Jos H

doi:https://doi.org/10.1016/j.jchromb.2016.09.012

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma

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Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma

Sparidans, Rolf W; Rosing, Hilde; Rood, Johannes J M; Schellens, Jan H M; Beijnen, Jos H

(2016) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, volume 1033-1034, pp. 390 - 398

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Keywords: Afatinib, Erlotinib, Gefitinib, Encorafenib, LC MS/MS, Plasma, Taverne

DOI: https://doi.org/10.1016/j.jchromb.2016.09.012

ISSN: 1570-0232

Publisher: Elsevier

(Peer reviewed)

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