Stamceltherapie voor het beschadigde hart

Abstract

Current therapies for ischemic heart failure are not sufficient. Regenerative therapy is a promising strategy that has rapidly developed into a clinical phase. Although the exact mechanism of action is not entirely understood, clinical results show a statistically significant effect of stem cells in ischemic heart diseases. At this moment there is no consensus on the clinical relevance of stem cell therapy. In this review we discuss the rationale for stem cell therapy. We will focus on autologous bone marrow cells in clinical setting. Finally, we will give an overview of new developments that will optimize future cell therapy.