Abstract
Objective:Both darunavir (DRV) and trimethoprim-sulfamethoxazole (TMP-SMX) carry a sulfonamide moiety and a warning for this cross-reactivity is given in the label of DRV. The aim of this study was to investigate the potential cross-reactivity between both drugs.Design:Retrospective cohort study with a nested case-control study.Methods:HIV-infected patients that received DRV-containing antiretroviral therapy
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