New interview and observation measures of the broader autism phenotype: group differentiation
de Jonge, Maretha; Parr, Jeremy; Rutter, Michael; Wallace, Simon; Kemner, Chantal; Bailey, Anthony; van Engeland, Herman; Pickles, Andrew
(2015) Journal of Autism and Developmental Disorders, volume 45, issue 4, pp. 893 - 901
(Article)
Abstract
To identify the broader autism phenotype (BAP), the Family History Interview subject and informant versions and an observational tool (Impression of Interviewee), were developed. This study investigated whether the instruments differentiated between parents of children with autism, and parents of children with Down syndrome (DS). The BAP scores of parents
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of 28 multiplex autism families were compared with parents from, 32 DS families. The BAP measures provided good group differentiation but when considered together, the subject interview did not improve group differentiation. The differentiation was better for fathers than mothers. The measures do carry an important degree of validity; whether they can differentiate the BAP from other social disorders should be tested.
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Keywords: Adolescent, Adult, Autistic Disorder, Child, Fathers, Female, Humans, Interview, Psychological, Male, Middle Aged, Mothers, Phenotype, Social Behavior, Young Adult, Broader autism phenotype, Group differentiation, Interview measures, Observational measures, Diagnosis
ISSN: 0162-3257
Publisher: Springer New York
(Peer reviewed)
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