Abstract
The combination of inhaled corticosteroids and
long-acting β2-adrenoceptor agonists is increasingly used
in chronic obstructive pulmonary disease (COPD). Recently,
we have demonstrated that combination of salmeterol
and fluticasone propionate (FP) additionally suppress the
production of IL-8 by human monocyte. In this study, the
molecular mechanism behind the effectiveness of this
combination therapy is investigated in human neutrophils.
Human
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