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Left Ventricle Myocardial Work Correlated with Functional Capacity in Severe Rheumatic Mitral Stenosis with Preserved Left Ventricular Ejection Fraction

Rudiktyo, Estu; Cramer, Maarten J.; Yonas, Emir; Teske, Arco J.; Siswanto, Bambang Budi; Doevendans, Pieter A.; Soesanto, Amiliana M. (Wolters Kluwer Medknow Publications, 2024-04)

Background and Aims: Functional capacity is reduced in mitral stenosis (MS) patients. Previous studies showed a correlation between left atrial strain and functional capacity in this population. However, currently, no left ...
Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours

Seiboldt, Till; Zeiser, Constantia; Nguyen, Duy; Celikyürekli, Simay; Herter, Sonja; Najafi, Sara; Stroh-Dege, Alexandra; Meulenbroeks, Chris; Mack, Norman; Salem-Altintas, Rabia; Westermann, Frank; Schlesner, Matthias; Milde, Till; Kool, Marcel; Holland-Letz, Tim; Vogler, Meike; Peterziel, Heike; Witt, Olaf; Oehme, Ina (Springer Nature, 2024-09)

Background: Certain paediatric nervous system malignancies have dismal prognoses. Retinoic acid (RA) is used in neuroblastoma treatment, and preclinical data indicate potential benefit in selected paediatric brain tumour ...
Author Correction: Respiratory syncytial virus infection and novel interventions (Nature Reviews Microbiology, (2023), 21, 11, (734-749), 10.1038/s41579-023-00919-w)

Langedijk, Annefleur C.; Bont, Louis J. (Nature Research, 2024-09)

In the version of this article initially published, there were typographical errors in the third paragraph of the “Preventive strategies” section, where in the text now reading “A single spontaneous mutation in the ...
The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomes

Füllbrunn, Nadia; Nicastro, Raffaele; Mari, Muriel; Griffith, Janice; Herrmann, Eric; Rasche, René; Borchers, Ann Christin; Auffarth, Kathrin; Kümmel, Daniel; Reggiori, Fulvio; De Virgilio, Claudio; Langemeyer, Lars; Ungermann, Christian (Rockefeller University Press, 2024-06-03)

Organelles of the endomembrane system contain Rab GTPases as identity markers. Their localization is determined by guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs). It remains largely unclear ...
Clinical effects of cannabis compared to synthetic cannabinoid receptor agonists (SCRAs): a retrospective cohort study of presentations with acute toxicity to European hospitals between 2013 and 2020

Waters, Mitchell L.; Dargan, Paul I.; Yates, Christopher; Dines, Alison M.; Eyer, Florian; Giraudon, Isabelle; Heyerdahl, Fridtjof; Hovda, Knut Erik; Liechti, Matthias E.; Miró, Òscar; Vallersnes, Odd Martin; Anseeuw, Kurt; Badaras, Robertas; Bitel, Marcin; Bonnici, Jeffrey; Brvar, Miran; Caganova, Blazena; Calýskan, Feriyde; Ceschi, Alessandro; Chamoun, Karam; Daveloose, Laurence; Galicia, Miguel; Gartner, Birgit; Gorozia, Ketevan; Grenc, Damjan; Gresnigt, Femke M.J.; Hondebrink, Laura; Jürgens, Gesche; Konstari, Jutta; Kutubidze, Soso; Laubner, Gabija; Liakoni, Evangelia; Liguts, Viesturs; Lyphout, Cathelijne; McKenna, Roy; Mégarbane, Bruno; Moughty, Adrian; Nitescu, Gabriela Viorela; Noseda, Roberta; O'Connor, Niall; Paasma, Raido; Ortega Perez, Juan; Perminas, Marius; Persett, Per Sverre; Põld, Kristiina; Puchon, Erik; Puiguriguer, Jordi; Radenkova-Saeva, Julia; Rulisek, Jan; Samer, Caroline; Schmid, Yasmin; Scholz, Irene; Stašinskis, Roberts; Surkus, Jonas; Van den Hengel-Koot, Irma; Vigorita, Federico; Vogt, Severin; Waldman, Wojciech; Waring, William Stephen; Zacharov, Sergej; Zellner, Tobias; Wood, David M. (Informa Healthcare, 2024-06)

Introduction: Cannabis is the most common recreational drug worldwide and synthetic cannabinoid receptor agonists are currently the largest group of new psychoactive substances. The aim of this study was to compare the ...
Risk assessment tools for bleeding in patients with unprovoked venous thromboembolism: an analysis of the PLATO-VTE study

Guman, Noori A.M.; Becking, Anne Marie L.; Weijers, Suzanne S.; Kraaijpoel, Noémie; Mulder, Frits I.; Carrier, Marc; Jara-Palomares, Luis; Di Nisio, Marcello; Ageno, Walter; Beyer-Westendorf, Jan; Klok, Frederikus A.; Vanassche, Thomas; Otten, Johannes M.M.B.; Cosmi, Benilde; Peters, Mike J.L.; Wolde, Marije ten; Delluc, Aurélien; Sanchez-Lopez, Veronica; Porreca, Ettore; Bossuyt, Patrick M.M.; Gerdes, Victor E.A.; Büller, Harry R.; van Es, Nick; Kamphuisen, Pieter W. (Wiley-Blackwell, 2024-09)

Background: Guidelines suggest indefinite anticoagulation after unprovoked venous thromboembolism (VTE) unless the bleeding risk is high, yet there is no consistent guidance on assessing bleeding risk. Objectives: This ...
Prevalence and 3-month follow-up of cerebrovascular MRI markers in hospitalized COVID-19 patients: the CORONIS study

van Lith, Theresa J.; Sluis, Wouter M.; Wijers, Naomi T.; Meijer, Frederick J.A.; Ulzen, Karin Kamphuis van; de Bresser, Jeroen; Dankbaar, Jan Willem; de Mast, Quirijn; Klok, Frederikus A.; Cannegieter, Suzanne C.; Wermer, Marieke J.H.; Huisman, Menno V.; Tuladhar, Anil M.; van der Worp, H. Bart; de Leeuw, Frank Erik (Springer-Verlag, 2024-09)

Purpose: To investigate the prevalence of cerebrovascular MRI markers in unselected patients hospitalized for COVID-19 (Coronavirus disease 2019), we compared these with healthy controls without previous SARS-CoV-2 infection ...
Practical Management of the JAK1 Inhibitor Abrocitinib for Atopic Dermatitis in Clinical Practice: Special Safety Considerations

Gooderham, Melinda J.; de Bruin-Weller, Marjolein; Weidinger, Stephan; Cork, Michael J.; Eichenfield, Lawrence F.; Simpson, Eric L.; Tsianakas, Athanasios; Kerkmann, Urs; Feeney, Claire; Romero, William (Springer-Verlag, 2024-08)

Abrocitinib, an oral, once-daily, Janus kinase (JAK) 1-selective inhibitor, is approved for the treatment of adults and adolescents with moderate-to-severe atopic dermatitis (AD). Abrocitinib has shown rapid and sustained ...
Object Tracking Based on Optical Flow Reconstruction of Motion-Group Parameters

Karpuzov, Simeon; Petkov, George; Ilieva, Sylvia; Petkov, Alexander; Kalitzin, Stiliyan (Multidisciplinary Digital Publishing Institute (MDPI), 2024-06)

Rationale. Object tracking has significance in many applications ranging from control of unmanned vehicles to autonomous monitoring of specific situations and events, especially when providing safety for patients with ...
IGF-1 Mediated Neuroprotective Effects of Olfactory-Derived Mesenchymal Stem Cells on Auditory Hair Cells

Lammers, Marc J.W.; Young, Emily; Yanai, Anat; Viringipurampeer, Ishaq A.; Le, Trung N.; Straatman, Louise V.; Westerberg, Brian D.; Gregory-Evans, Kevin (2024)

IMPORTANCE: Mesenchymal stem cells (MSCs) have the capability of providing ongoing paracrine support to degenerating tissues. Since MSCs can be extracted from a broad range of tissues, their specific surface marker profiles ...
RPA3-UMAD1 rs12702634 and rheumatoid arthritis–associated interstitial lung disease in European ancestry

Juge, Pierre Antoine; Sparks, Jeffrey A.; Gazal, Steven; Ebstein, Esther; Borie, Raphaël; Debray, Marie Pierre; Kannengiesser, Caroline; McDermott, Gregory C.; Cui, Jing; Hayashi, Keigo; Doyle, Tracy J.; van Moorsel, Coline H.M.; van der Vis, Joanne J.; Grutters, Jan C.; Knevel, Rachel; Heckert, Sascha L.; Vasarmidi, Eirini; Antoniou, Katerina M.; van der Helm van Mil, Annette H.M.; Boileau, Catherine; Crestani, Bruno; Dieudé, Philippe (Oxford University Press, 2024)

Objective: Recently, a genome-wide association study identified an association between RA-associated interstitial lung disease (ILD) and RPA3-UMAD1 rs12702634 in the Japanese population, especially for patients with a usual ...
Impact of ciprofloxacin prophylaxis on blood stream infection during early treatment phase of pediatric acute lymphoblastic leukemia: An observational cohort study

Scharloo, Fenna; Wolfs, Tom F.W.; van der Bruggen, Tjomme; van der Sluis, Inge M.; Tissing, Wim J.E.; de Vrankrijker, Angelica M.M. (Elsevier, 2024-06)

Purpose: Data on the efficacy of antibiotic prophylaxis in children with acute lymphoblastic leukemia (ALL) is scarce and recent guidelines advise against its use. This study is conducted to evaluate if the use of ciprofloxacin ...
Association between work sick-leave absenteeism and SARS-CoV-2 notifications in the Netherlands during the COVID-19 epidemic

Keet, Martijn G.; Boudewijns, Bronke; Jongenotter, Femke; van Iersel, Senna; van Werkhoven, Cornelis H.; van Gageldonk-Lafeber, Rianne B.; Wisse, Bram W.; van Asten, Liselotte (2024-06-01)

Background: Alternative data sources for surveillance have gained importance in maintaining coronavirus disease 2019 (COVID-19) situational awareness as nationwide testing has drastically decreased. Therefore, we explored ...
Productivity costs of lifelong smoking—the Northern Finland Birth Cohort 1966 study

Rissanen, Ina; Nerg, Iiro; Oura, Petteri; Huikari, Sanna; Korhonen, Marko (2024-06-01)

Background: Smoking is one of the leading causes of impaired health and mortality. Loss of paid and unpaid work and replacements due to morbidity and mortality result in productivity costs. Our aim was to investigate the ...
Global disparities in caesarean section rates: Why indication-based metrics are needed

Zaigham, Mehreen; Varallo, John; Thangaratinam, Shakila; Nicholson, Wanda; Visser, Gerard H.A. (Public Library of Science, 2024-02)
Assisted peritoneal dialysis in Europe: a strategy to increase and maintain home dialysis

Reyskens, Margot; Abrahams, Alferso C.; François, Karlien; Van Eck Van Der Sluijs, Anita (Oxford University Press, 2024-05-01)

Peritoneal dialysis (PD) is a form of kidney replacement therapy with the major advantage that it can be performed at home. This has a positive impact on patients' autonomy and quality of life. However, the dialysis ...
Clinical evidence and technical aspects of innovative technology and monitoring of chronic NIV in COPD: a narrative review

Soleimani, F; Donker, D W; Oppersma, E; Duiverman, M L (Taylor and Francis Ltd., 2024-07)

INTRODUCTION: Chronic nocturnal noninvasive ventilation (NIV) improves outcomes in COPD patients with chronic hypercapnic respiratory failure. The aim of chronic NIV in COPD is to control chronic hypercapnic respiratory ...
Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations

Okonechnikov, Konstantin; Schrimpf, Daniel; Koster, Jan; Sievers, Philipp; Milde, Till; Sahm, Felix; Jones, David T.W.; von Deimling, Andreas; Pfister, Stefan M.; Kool, Marcel; Korshunov, Andrey (Springer, 2024-06)

The non-WNT/non-SHH (Grp3/Grp4) medulloblastomas (MBs) include eight second-generation subgroups (SGS; I–VIII) each with distinct molecular and clinical characteristics. Recently, we also identified two prognostically ...
Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020

Kayode, Gbenga A.; Vision Loss Expert Group of the Global Burden of Disease Study; the GBD 2019 Blindness and Vision Impairment Collaborators (Springer Nature, 2024-08)

Background: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by cataract and their proportion of the total number of vision-impaired individuals. Methods: A systematic ...
The Association of Plasma Leptin, Soluble Leptin Receptor and Total and High-Molecular Weight Adiponectin With the Risk of Perioperative Neurocognitive Disorders

Feinkohl, Insa; Janke, Jürgen; Slooter, Arjen J C; Winterer, Georg; Spies, Claudia; Pischon, Tobias (Lippincott Williams & Wilkins, 2024-09)

Background: Perioperative neurocognitive disorders (NCD) are poorly characterized in terms of their risk factor profiles. Leptin and adiponectin are adipose-tissue-derived hormones with a role in inflammation and atherosclerosis ...

Now showing items 5081-5100 of 40729